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SOCS5 抗体 (N-Term)

SOCS5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855921
发货至: 中国
  • 抗原 See all SOCS5 抗体
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    抗原表位
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 29
    • 3
    • 2
    人, 小鼠
    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS5 antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    大鼠, 猪, 小鸡, 猕猴, 牛
    交叉反应 (详细)
    Rat (100 %), Pig (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)
    产品特性
    Rabbit Polyclonal antibody to SOCS5 (suppressor of cytokine signaling 5)
    SOCS5 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOCS5. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: Molt-4 , NT2D1 , PC-3 , mouse testis

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Cui, Chen, Zhang, Cheng, Pan, Huang, Hu, Zhang, Wang, Zhu, Chen, Liu, Zhao, Wu, Yang, Liu, Zhang, Yu, Yin, Jing, Rehman, Tian, Pan, Jia: "Duck Tembusu Virus Utilizes miR-221-3p Expression to Facilitate Viral Replication via Targeting of Suppressor of Cytokine Signaling 5." in: Frontiers in microbiology, Vol. 11, pp. 596, (2020) (PubMed).

    Tsai, Kuo, Hung, Wu, Wu, Chang, Kuo, Hsu: "Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy." in: Molecular therapy. Nucleic acids, Vol. 13, pp. 543-555, (2018) (PubMed).

  • 抗原
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    别名
    SOCS5 (SOCS5 产品)
    别名
    SOCS5 antibody, cis6 antibody, cish5 antibody, cish6 antibody, socs-5 antibody, GB18949 antibody, socs5 antibody, zgc:153506 antibody, CIS6 antibody, CISH6 antibody, Cish5 antibody, SOCS-5 antibody, 1810018L08Rik antibody, mKIAA0671 antibody, RGD1564914 antibody, suppressor of cytokine signaling 5 antibody, suppressor of cytokine signaling 5a antibody, suppressor of cytokine signaling 5 L homeolog antibody, SOCS5 antibody, socs5 antibody, LOC552036 antibody, socs5a antibody, Tsp_07018 antibody, socs5.L antibody, Socs5 antibody
    背景
    The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

    分子量
    61 kDa
    基因ID
    9655
    途径
    JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
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