电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SOCS5 抗体 (AA 1-270)

SOCS5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7171007
发货至: 中国
  • 抗原 See all SOCS5 抗体
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    抗原表位
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-270
    适用
    • 29
    • 4
    • 2
    宿主
    • 25
    • 3
    • 1
    克隆类型
    • 28
    • 1
    多克隆
    标记
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS5 antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 13
    • 8
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Suppressor of cytokine signaling 5 protein (1-270AA)
    亚型
    IgG
    Top Product
    Discover our top product SOCS5 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
    别名
    SOCS5 (SOCS5 产品)
    别名
    SOCS5 antibody, cis6 antibody, cish5 antibody, cish6 antibody, socs-5 antibody, GB18949 antibody, socs5 antibody, zgc:153506 antibody, CIS6 antibody, CISH6 antibody, Cish5 antibody, SOCS-5 antibody, 1810018L08Rik antibody, mKIAA0671 antibody, RGD1564914 antibody, suppressor of cytokine signaling 5 antibody, suppressor of cytokine signaling 5a antibody, suppressor of cytokine signaling 5 L homeolog antibody, SOCS5 antibody, socs5 antibody, LOC552036 antibody, socs5a antibody, Tsp_07018 antibody, socs5.L antibody, Socs5 antibody
    背景

    Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T-helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes differentiation into the Th2 phenotype. Can also partially inhibit IL6 and LIF signaling.

    Aliases: SOCS5 antibody, CIS6 antibody, CISH5 antibody, CISH6 antibody, KIAA0671Suppressor of cytokine signaling 5 antibody, SOCS-5 antibody, Cytokine-inducible SH2 protein 6 antibody, CIS-6 antibody, Cytokine-inducible SH2-containing protein 5 antibody

    UniProt
    O75159
    途径
    JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
You are here: