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Melanoma gp100 抗体 (AA 376-502)

The 小鼠 单克隆 anti-Melanoma gp100 antibody is suitable to detect Melanoma gp100 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7874472
发货至: 中国
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Quick Overview for Melanoma gp100 抗体 (AA 376-502) (ABIN7874472)

抗原

See all Melanoma gp100 (PMEL) 抗体
Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Melanoma gp100 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

MSSG95-2
  • 抗原表位

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    AA 376-502

    原理

    Melanoma gp100 Antibody / PMEL17

    纯化方法

    Protein G affinity chromatography

    免疫原

    A portion of amino acids 376-502 from the human protein was used as the immunogen for the Melanoma gp100 antibody.

    亚型

    IgG1, kappa
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the Melanoma gp100 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Melanoma gp100 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))

    别名

    Melanoma gp100

    背景

    PMEL17/Melanoma gp100/SILV plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. [UniProt]

    UniProt

    P40967
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