MSH2 抗体 (AA 337-583)
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Quick Overview for MSH2 抗体 (AA 337-583) (ABIN7874055)
抗原
See all MSH2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 337-583
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原理
- MSH2 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human MSH2 protein (amino acids Q337-N583) was used as the immunogen for the MSH2 antibody.
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亚型
- IgG2b
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应用备注
- Optimal dilution of the MSH2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MSH2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MSH2 (Mismatch Repair Protein 2 (MSH2))
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别名
- MSH2
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背景
- DNA mismatch repair protein Msh2, also known as MutS protein homolog 2 or MSH2, is a protein that in humans is encoded by the MSH2 gene, which is located on chromosome 2. MSH2 is a tumor suppressor gene and more specifically a caretaker gene that codes for a DNA mismatch repair (MMR) protein, MSH2 which forms a heterodimer with MSH6 to make the human MutS-alpha mismatch repair complex. It also dimerizes with MSH3 to form the MutS-beta DNA repair complex. MSH2 is involved in many different forms of DNA repair, including transcription-coupled repair, homologous recombination, and base excision repair. It has been found that MSH2 may also be a coactivator of ESR1-dependent gene expression.
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UniProt
- P43246
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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