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Connexin 43/GJA1 抗体 (AA 3-362)

The 兔 多克隆 anti-Connexin 43/GJA1 antibody is suitable to detect Connexin 43/GJA1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 IHC (p).
产品编号 ABIN7873539
发货至: 中国
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Quick Overview for Connexin 43/GJA1 抗体 (AA 3-362) (ABIN7873539)

抗原

See all Connexin 43/GJA1 (GJA1) 抗体
Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

适用

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人, 小鼠, 大鼠

宿主

  • 134
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克隆类型

  • 136
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多克隆

标记

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This Connexin 43/GJA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 3-362

    原理

    Connexin 43 Antibody

    纯化方法

    Affinity purified

    免疫原

    A human recombinant protein (amino acids D3-R362) was used as the immunogen for the Connexin 43 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Connexin 43 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Connexin 43 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

    别名

    Connexin 43

    背景

    Connexin 43 (Cx43), also called GAP Junction Protein, alpha-1 (GJA1). Connexin 43 is a member of the connexin gene family which abundantly expressed in the heart and liver and was mapped to 6q21-q23.2. Connexin43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Mutations in the connexin 43 gap-junction gene, which lead to abnormally regulated cell-cell communication, are associated with visceroatrial heterotaxia. Cx43 must also play a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.

    UniProt

    P17302

    途径

    MAPK Pathway, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization
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