TIA1 抗体 (AA 279-380)
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北京 101111
Quick Overview for TIA1 抗体 (AA 279-380) (ABIN7873218)
抗原
See all TIA1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 279-380
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原理
- TIA1 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- Amino acids 279-380 from the human protein were used as the immunogen for the TIA1 antibody.
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亚型
- IgG2b, kappa
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anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibody
TIA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 3A3B9 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-193) antibodyTIA1 适用: 人 WB, IHC, ELISA, IP 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-215) antibodyTIA1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2A10B12 unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyKD Validated TIA1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB2175 unconjugated Recombinant Antibody
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyVerified TIA1 适用: 人 WB, IHC, IF, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) antibodyTIA1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (AA 1-214) antibodyTIA1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (Internal Region) antibodyTIA1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1) (C-Term) antibodyTIA1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the TIA1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the TIA1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))
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别名
- TIA1
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背景
- TIA-1 (T-cell intracytoplasmic antigen) is a cytoplasmic granule-associated protein, expressed in lymphocytes processing cytolytic potential. TIA-1 is a member of an RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15 kDa protein thought to be derived from the carboxyl terminus of the 40 kDa product by proteolytic processing. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.
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UniProt
- P31483
抗原
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