YBX1 抗体 (AA 275-310)
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Quick Overview for YBX1 抗体 (AA 275-310) (ABIN7873204)
抗原
See all YBX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 275-310
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原理
- Zebrafish Yb-1 Antibody / Ybx1 / Y-box-binding protein 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Yb-1 recombinant protein (amino acids R275-D310) was used as the immunogen for the Zebrafish Yb-1 antibody.
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亚型
- Ig Fraction
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anti-Y Box Binding Protein 1 (YBX1) (AA 100-200) antibody
YBX1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 WB, IHC, IF, IP, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 293-320), (C-Term) antibodyYBX1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (Middle Region) antibodyYBX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 兔, 绵羊, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 51-139) antibodyYBX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人 IHC 宿主: 小鼠 Monoclonal YBX1-2430 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 224-274) antibodyYBX1 适用: 人, 小鼠 WB, IHC (fp), IP 宿主: 兔 Polyclonal unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 276-305), (C-Term) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB14114 unconjugated
anti-Y Box Binding Protein 1 (YBX1) (AA 149-178) antibodyYBX1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41913 unconjugated
anti-Y Box Binding Protein 1 (YBX1) antibodyYBX1 适用: 人, 大鼠, 小鼠, Cow, 犬, 小鸡, Pig WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Yb-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Yb-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- YBX1 (Y Box Binding Protein 1 (YBX1))
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别名
- Yb-1
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背景
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Y-box binding protein 1 (Ybx1, Yb-1) is a multifunctional RNA- and DNA-binding protein conserved across vertebrates. In zebrafish, Yb-1 plays a critical role in early embryogenesis, cellular proliferation, and gene regulation. The protein contains a conserved cold shock domain (CSD) that facilitates binding to nucleic acids, enabling Yb-1 to modulate transcription, mRNA splicing, stability, and translation.
Biological Function:
Yb-1 is essential for zebrafish embryonic development. Knockdown or mutation of Yb-1 results in early embryonic lethality due to impaired morphogenesis, suggesting a key regulatory role in zygotic gene activation and maternal RNA clearance. It is also involved in stress responses, regulation of cell cycle genes, and may contribute to sex determination pathways in zebrafish.Expression Pattern:
Yb-1 is maternally deposited and ubiquitously expressed during early embryonic stages. As development progresses, its expression becomes more tissue-specific, particularly enriched in proliferative zones and neural tissues.Orthology and Conservation:
Zebrafish Ybx1 is orthologous to human YBX1, sharing high sequence similarity and functional conservation. This makes zebrafish a valuable model for studying YBX1-related roles in development and disease, including cancer biology and RNA regulation. -
UniProt
- B5DE31
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途径
- Regulation of Muscle Cell Differentiation
抗原
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