FLT1 抗体 (AA 27-73)
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Quick Overview for FLT1 抗体 (AA 27-73) (ABIN7873143)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-73
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原理
- VEGFR-1 Antibody / FLT1
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids S27-R73) was used as the immunogen for the VEGFR-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the VEGFR-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the VEGFR-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- VEGFR-1
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背景
- Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene. This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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