FLT1 抗体 (AA 27-399)
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Quick Overview for FLT1 抗体 (AA 27-399) (ABIN7873118)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-399
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原理
- VEGFR1 Antibody / FLT1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids S27-D399) was used as the immunogen for the VEGFR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the VEGFR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the VEGFR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- VEGFR1
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背景
- Vascular endothelial growth factor receptor 1 (FLT1) is a protein that in humans is encoded by the FLT1 gene. Oncogene FLT belongs to the src gene family. It is mapped to 13q12. The deduced 1,338-amino acid protein has a calculated molecular mass of 150.6 kD. It has a 758-amino acid extracellular domain, followed by a 22-amino acid transmembrane region and a 558-amino acid cytoplasmic region containing a cluster of basic amino acids and a tyrosine kinase domain. sFLT-1 was identified in placenta, adult lung, kidney, liver and uterus. Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation.
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UniProt
- P17948
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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