BDNF 抗体 (AA 27-278)
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Quick Overview for BDNF 抗体 (AA 27-278) (ABIN7873108)
抗原
See all BDNF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 27-278
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原理
- Zebrafish Bdnf Antibody / Brain-derived neurotrophic factor
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纯化方法
- Antigen affinity chromatography
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免疫原
- E. coli-derived zebrafish Bdnf recombinant protein (amino acids A27-R278) was used as the immunogen for the Zebrafish Bdnf antibody.
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亚型
- Ig Fraction
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anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibody
BDNF 适用: Pig WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 19-248) antibodyBDNF 适用: 人 WB, ICC, ELISA 宿主: 小鼠 Monoclonal 3D9C5 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 151-247) antibodyBDNF 适用: 人, 大鼠, 小鼠 WB, ICC, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 20-252) antibodyBDNF 适用: Pig WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 1-247) antibodyBDNF 适用: 人 WB, IP, ELISA, IF 宿主: 小鼠 Monoclonal 1B10 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (Internal Region) antibodyVerified BDNF 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236), (C-Term) antibodyBDNF 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB14839 unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibodyBDNF 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 206-236) antibodyBDNF 适用: 人 WB, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Brain-Derived Neurotrophic Factor (BDNF) (AA 129-247) antibodyBDNF 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Zebrafish Bdnf antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Bdnf antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BDNF (Brain-Derived Neurotrophic Factor (BDNF))
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别名
- Bdnf
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背景
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Brain-derived neurotrophic factor (Bdnf) is a key member of the neurotrophin family, which plays a vital role in the development, maintenance, and plasticity of the nervous system. In zebrafish (Danio rerio), the bdnf gene encodes a protein highly conserved with its mammalian counterpart, sharing significant sequence and functional homology. Bdnf is critically involved in promoting the survival and differentiation of neurons, synaptic plasticity, and modulation of neurogenesis during development and in the adult brain.
Expression of Bdnf in zebrafish is observed early in embryogenesis and persists in various regions of the central nervous system, including the forebrain, optic tectum, and spinal cord. Zebrafish Bdnf interacts primarily with the high-affinity receptor TrkB (Ntrk2), activating intracellular signaling pathways such as PI3K-Akt, MAPK/ERK, and PLC-i³, which are essential for neurotrophic support and synaptic function.
Due to the genetic tractability and optical transparency of zebrafish embryos, this model organism is widely used to investigate Bdnf-mediated neuronal development, behavior, and regeneration. Studies have also linked altered bdnf expression to stress responses, learning, and memory in zebrafish, highlighting its relevance in neurodevelopmental and neuropsychiatric research.
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途径
- RTK signaling, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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