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Tyrosinase-Related Protein 1 抗体 (AA 257-377)

This 小鼠 单克隆 antibody specifically detects Tyrosinase-Related Protein 1 in ELISA 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7872962
发货至: 中国
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (AA 257-377) (ABIN7872962)

抗原

See all Tyrosinase-Related Protein 1 (TYRP1) 抗体
Tyrosinase-Related Protein 1 (TYRP1)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Tyrosinase-Related Protein 1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TYRP1-3280
  • 抗原表位

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    AA 257-377

    原理

    Tyrosinase-Related Protein-1 Antibody / TRP1 / TYRP1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this Tyrosinase-Related Protein-1 antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Tyrosinase-Related Protein-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Tyrosinase-Related Protein 1 (TYRP1)

    别名

    Tyrosinase-Related Protein-1

    背景

    It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

    UniProt

    P17643
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