Tyrosinase-Related Protein 1 抗体 (AA 257-377)
Our Local Distributor
北京 101111
Quick Overview for Tyrosinase-Related Protein 1 抗体 (AA 257-377) (ABIN7872962)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 257-377
-
原理
- Tyrosinase-Related Protein-1 Antibody / TRP1 / TYRP1
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this Tyrosinase-Related Protein-1 antibody.
-
亚型
- IgG2b, kappa
-
-
-
-
应用备注
- Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the Tyrosinase-Related Protein-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- Tyrosinase-Related Protein 1 (TYRP1)
-
别名
- Tyrosinase-Related Protein-1
-
背景
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
-
UniProt
- P17643
抗原
-