Tyrosinase-Related Protein 1 抗体 (AA 257-377)
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Quick Overview for Tyrosinase-Related Protein 1 抗体 (AA 257-377) (ABIN7872959)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 257-377
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原理
- Tyrosinase-Related Protein-1 Antibody / TRP1 / TYRP1 (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 257-377) was used as the immunogen for this TRP1 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the Tyrosinase-Related Protein-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- Tyrosinase-Related Protein-1
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背景
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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UniProt
- P17643
抗原
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