IGKV1-27 抗体 (AA 241-356)
The 小鼠 单克隆 anti-IGKV1-27 antibody is suitable to detect IGKV1-27 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872741
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for IGKV1-27 抗体 (AA 241-356) (ABIN7872741)
抗原
See all IGKV1-27 抗体
IGKV1-27
(Immunoglobulin kappa Variable 1-27 (IGKV1-27))
适用
人
宿主
小鼠
克隆类型
单克隆
标记
This IGKV1-27 antibody is un-conjugated
应用范围
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
质量等级
Carrier-free
克隆位点
TNFAIP3-2813
-
-
抗原表位
- AA 241-356
-
原理
- A20 Antibody / TNFAIP3 (azide and preservative free)
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A portion of amino acids 241-356 from the human protein was used as the immunogen for the A20 antibody.
-
亚型
- IgG2c, kappa
-
-
anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Internal Region) antibody
IGKV1-27 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin kappa Variable 1-27 (IGKV1-27) (Center) antibodyIGKV1-27 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal dilution of the A20 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
储存液
- Azide free
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the A20 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- IGKV1-27 (Immunoglobulin kappa Variable 1-27 (IGKV1-27))
-
别名
- A20
-
背景
- A20 (also known as TNFAIP3) is a zinc finger protein and inhibits NF-kappa B activation as well as TNF-mediated apoptosis. The protein has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. A20 is as a tumor suppressor and has been shown to protect MCF-7 breast carcinoma cells from TNF-induced apoptosis. High A20 expression levels were observed in more aggressive breast tumors (ER-negative, progesterone receptor-negative and high histological grade). These findings strongly suggest that A20 is a key protein involved in tamoxifen resistance.
-
UniProt
- P21580
-
途径
- Activation of Innate immune Response
抗原
-
You are here:
