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FcRn 抗体 (AA 24-215)

The 小鼠 单克隆 anti-FcRn antibody is suitable to detect FcRn in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872675
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FcRn 抗体 (AA 24-215) (ABIN7872675)

抗原

See all FcRn 抗体
FcRn (neonatal Fc Receptor (FcRn))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FcRn antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

FCGRT-2932
  • 抗原表位

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    AA 24-215

    原理

    FCGRT Antibody / FcRn

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 24-215) was used as the immunogen for the FCGRT antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the FCGRT antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the FCGRT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    FcRn (neonatal Fc Receptor (FcRn))

    别名

    FCGRT

    背景

    This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.

    UniProt

    P55899

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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