FcRn 抗体 (AA 24-215)
Our Local Distributor
北京 101111
Quick Overview for FcRn 抗体 (AA 24-215) (ABIN7872675)
抗原
See all FcRn 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 24-215
-
原理
- FCGRT Antibody / FcRn
-
纯化方法
- Protein G affinity chromatography
-
免疫原
- A recombinant human partial protein (amino acids 24-215) was used as the immunogen for the FCGRT antibody.
-
亚型
- IgG2b, kappa
-
-
-
-
应用备注
- Optimal dilution of the FCGRT antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.2 mg/mL
-
缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store the FCGRT antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- FcRn (neonatal Fc Receptor (FcRn))
-
别名
- FCGRT
-
背景
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
-
UniProt
- P55899
-
途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
-