FcRn 抗体 (AA 24-215)
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北京 101111
Quick Overview for FcRn 抗体 (AA 24-215) (ABIN6939380)
抗原
See all FcRn 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 24-215
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原理
- FCGRT / FcRn (IgG Transporter) Antibody
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特异性
- This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment of human FCGRT protein (around aa 24-215) (Exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-neonatal Fc Receptor (FcRn) antibody
FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
anti-neonatal Fc Receptor (FcRn) antibodyFcRn 适用: 人 ELISA, IF, FACS, cELISA 宿主: 小鼠 Monoclonal DVN24 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-365) antibodyFcRn 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F3D1 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 24-297) antibodyFcRn 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2B3B11 unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 54-291) antibodyFcRn 适用: 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 25-300) antibodyFcRn 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (AA 56-291) antibodyFcRn 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-neonatal Fc Receptor (FcRn) (N-Term) antibodyFcRn 适用: 人, 小鼠, Cow, 犬, 豚鼠, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: THP1 or HepG2 cells. Cerebellum or Testis.
Known Application: Immunohistochemistry (Formalin-fixed) (2-4 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- FcRn (neonatal Fc Receptor (FcRn))
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别名
- FCGRT
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背景
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Fc fragment of IgG, receptor transporter, alpha, FCGRT, FCRN, alpha chain, IgG Fc fragment receptor transporter alpha chain, IgG Gc receptor, IgG receptor FcRn large subunit p51, Immunoglobulin receptor, intestinal, heavy chain, Neonatal Fc receptor
THP1 or HepG2 cells. Cerebellum or Testis.
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分子量
- 46kDa
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基因ID
- 2217, 111903
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UniProt
- P55899
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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