MR1 抗体 (AA 23-269)
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Quick Overview for MR1 抗体 (AA 23-269) (ABIN7872521)
抗原
See all MR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-269
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原理
- MR1 Antibody / MHC class I related protein 1
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids R23-D269 from the human protein were used as the immunogen for the MR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
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别名
- MR1
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背景
- Major histocompatibility complex class I-related gene protein is a protein that in humans is encoded by the MR1 gene. MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
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UniProt
- Q95460
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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