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TIM3 抗体 (AA 22-202)

This 小鼠 单克隆 antibody specifically detects TIM3 in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7872311
发货至: 中国
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Quick Overview for TIM3 抗体 (AA 22-202) (ABIN7872311)

抗原

See all TIM3 (TIM 3) 抗体
TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

适用

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宿主

  • 74
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小鼠

克隆类型

  • 136
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单克隆

标记

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This TIM3 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TMDP3-1
  • 抗原表位

    • 62
    • 7
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    AA 22-202

    原理

    TIM3 Antibody / HAVCR2

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant fragment of human TIM3 protein within amino acids 22-202 was used as the immunogen for the TIM3 antibody.

    亚型

    IgG2a, kappa
  • 应用备注

    Optimal dilution of the TIM3 antibody should be determined by the researcher.
    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the TIM3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

    别名

    TIM3

    背景

    The protein encoded by the HAVCR2 gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [RefSeq]

    UniProt

    Q8TDQ0

    途径

    Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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