NOTCH2 抗体 (AA 2194-2471)
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Quick Overview for NOTCH2 抗体 (AA 2194-2471) (ABIN7872263)
抗原
See all NOTCH2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2194-2471
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原理
- NOTCH2 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids H2194-A2471) was used as the immunogen for the NOTCH2 antibody.
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亚型
- IgG
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anti-Notch 2 (NOTCH2) antibody
NOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (Asp1733), (cleaved) antibodyNOTCH2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (C-Term) antibodyNOTCH2 适用: 人, 小鼠 WB, ChIP-seq 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 1501-1700) antibodyNOTCH2 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2251-2466) antibodyNOTCH2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 59-250) antibodyNOTCH2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (cleaved), (Internal Region) antibodyNOTCH2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2242-2471) antibodyNOTCH2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2421-2471) antibodyNOTCH2 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Notch 2 (NOTCH2) (AA 2250-2300) antibodyNOTCH2 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the NOTCH2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NOTCH2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NOTCH2 (Notch 2 (NOTCH2))
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别名
- NOTCH2
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背景
- Neurogenic locus notch homolog protein 2 also known as notch 2 is a protein that in humans is encoded by the NOTCH2 gene. It is mapped to 1p12. This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q04721
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途径
- Notch Signaling, Stem Cell Maintenance
抗原
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