Recombinant Tyrosinase-Related Protein 1 抗体 (AA 200-400)
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Quick Overview for Recombinant Tyrosinase-Related Protein 1 抗体 (AA 200-400) (ABIN7872065)
抗原
See all Tyrosinase-Related Protein 1 (TYRP1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-400
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原理
- Tyrosinase-Related Protein-1 Antibody / TYRP1
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纯化方法
- Protein A affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the Tyrosinase-Related Protein-1 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Tyrosinase-Related Protein-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Tyrosinase-Related Protein-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Tyrosinase-Related Protein 1 (TYRP1)
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别名
- Tyrosinase-Related Protein-1
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背景
- It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
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UniProt
- P17643
抗原
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