电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TCF7 抗体 (AA 200-400)

The 小鼠 单克隆 anti-TCF7 antibody is suitable to detect TCF7 in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7872063
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TCF7 抗体 (AA 200-400) (ABIN7872063)

抗原

See all TCF7 抗体
TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

适用

  • 62
  • 41
  • 18
  • 7
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1

宿主

  • 54
  • 11
  • 1
小鼠

克隆类型

  • 52
  • 14
单克隆

标记

  • 44
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This TCF7 antibody is un-conjugated

应用范围

  • 45
  • 21
  • 19
  • 9
  • 6
  • 4
  • 4
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

TCF7-7631
  • 抗原表位

    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-400

    原理

    TCF7 Antibody / Transcription Factor 7

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 200-400) from the human protein was used as the immunogen for the TCF7 antibody.

    亚型

    IgG2, kappa
  • 应用备注

    Optimal dilution of the TCF7 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the TCF7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

    别名

    TCF7

    背景

    Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages (By similarity). Required for the development of natural killer receptor-positive lymphoid tissue inducer T-cells (By similarity). TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes.

    UniProt

    P36402

    途径

    WNT signaling
You are here: