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Thrombospondin 1 抗体 (AA 19-268)

The 兔 多克隆 anti-Thrombospondin 1 antibody is suitable to detect Thrombospondin 1 in samples from 人. It has been validated for WB, ELISA 和 FACS.
产品编号 ABIN7871580
发货至: 中国
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Quick Overview for Thrombospondin 1 抗体 (AA 19-268) (ABIN7871580)

抗原

See all Thrombospondin 1 (THBS1) 抗体
Thrombospondin 1 (THBS1)

适用

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宿主

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克隆类型

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多克隆

标记

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This Thrombospondin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 19-268

    原理

    THBS1 Antibody / Thrombospondin

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids N19-A268) was used as the immunogen for the THBS1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the THBS1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the THBS1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Thrombospondin 1 (THBS1)

    别名

    THBS1

    背景

    THBS1 is also known as Thrombospondin 1, TSP1. The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. It is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Also this protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. In addition, the thrombospondin-1 protein is a member of the thrombospondinfamily. It is a multi-domain matrix glycoprotein that has been shown to be a natural inhibitor of neovascularization and tumorigenesis in healthy tissue. Both positive and negative modulation of endothelial cell adhesion, motility, and growth have been attributed to TSP1. This should not be surprising considering that TSP1 interacts with at least 12 cell adhesion receptors, including CD36, ?v integrins, ?1 integrins, syndecan, and integrin-associated protein (IAP or CD47). It also interacts with numerous proteases involved in angiogenesis, including plasminogen, urokinase, matrix metalloproteinase, thrombin, cathepsin, and elastase.

    UniProt

    P07996

    途径

    Autophagy
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