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MUTYH 抗体 (AA 187-528)

This 兔 多克隆 antibody specifically detects MUTYH in WB, ELISA 和 FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7871513
发货至: 中国
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Quick Overview for MUTYH 抗体 (AA 187-528) (ABIN7871513)

抗原

See all MUTYH 抗体
MUTYH (MutY Homolog (E. Coli) (MUTYH))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MUTYH antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

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    AA 187-528

    原理

    MUTYH Antibody / Adenine DNA glycosylase / MYH1

    纯化方法

    Antigen affinity purified

    免疫原

    An E.coli-derived human recombinant protein (amino acids A187-N528) was used as the immunogen for the MUTYH antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the MUTYH antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the MUTYH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MUTYH (MutY Homolog (E. Coli) (MUTYH))

    别名

    MUTYH

    背景

    This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.

    UniProt

    Q9UIF7

    途径

    DNA Damage Repair
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