CCR2 抗体 (AA 18-53)
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Quick Overview for CCR2 抗体 (AA 18-53) (ABIN7871428)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-53
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原理
- CCR2 Antibody
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids E18-F53) was used as the immunogen for the CCR2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CCR2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the CCR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CCR2
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背景
- C-C chemokine receptor type 2 (CCR2 or CD192 (cluster of differentiation 192) is a protein that in humans is encoded by the CCR2 gene. It is mapped to 3p21.31. The protein encoded by this gene is a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The encoded protein mediates agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This protein can also be a coreceptor with CD4 for HIV-1 infection.
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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