HNF4A 抗体 (AA 164-474)
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北京 101111
Quick Overview for HNF4A 抗体 (AA 164-474) (ABIN7871132)
抗原
See all HNF4A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 164-474
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原理
- HNF4A Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q164-I474) was used as the immunogen for the HNF4A antibody.
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亚型
- IgG2a
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anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 324-423) antibody
HNF4A 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyHNF4A 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (pSer313) antibodyHNF4A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) antibodyHNF4A 适用: 小鼠 WB, IHC, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 1-464) antibodyHNF4A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 200-300) antibodyHNF4A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (AA 281-312) antibodyHNF4A 适用: 人, 大鼠 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB17745 unconjugated
anti-Hepatocyte Nuclear Factor 4, alpha (HNF4A) (N-Term) antibodyVerified HNF4A 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- Optimal dilution of the HNF4A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the HNF4A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))
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别名
- HNF4A
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背景
- Hepatocyte nuclear factor 4 alpha (HNF4A), also known as NR2A1, is a nuclear receptor that in humans is encoded by the HNF4A gene. It is mapped to 20q13.12. HNF4A is a nuclear transcription factor that binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene plays a role in development of the liver, kidney, and intestines. HNF4A is required for the PXR and CAR-mediated transcriptional activation of CYP3A4. This gene also plays a pivotal role in the expression and synthesis of SHBG, an important glycoprotein made primarily in the liver, which in addition to lowering insulin-resistance also serves in reducing levels of free Oestrogen as-well as prolonging the half-life of Testosterone.
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UniProt
- P41235
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途径
- AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process
抗原
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