RYK 抗体 (AA 160-190)
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Quick Overview for RYK 抗体 (AA 160-190) (ABIN7871095)
抗原
See all RYK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-190
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原理
- RYK Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 160-190 from the human protein were used as the immunogen for the RYK antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the RYK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RYK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RYK (RYK Receptor-Like Tyrosine Kinase (RYK))
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别名
- RYK
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背景
- RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.
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UniProt
- P34925
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途径
- RTK signaling, WNT signaling, Regulation of Cell Size
抗原
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