BAI1 抗体 (AA 1537-1567)
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北京 101111
Quick Overview for BAI1 抗体 (AA 1537-1567) (ABIN7870991)
抗原
See all BAI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1537-1567
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原理
- Brain-specific angiogenesis inhibitor 1 Antibody / BAI1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 1537-1567 from the human protein was used as the immunogen for the Brain-specific angiogenesis inhibitor 1 antibody.
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亚型
- Ig Fraction
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anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 1537-1567), (C-Term) antibody
BAI1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB02096 unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) antibodyBAI1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (Internal Region) antibodyBAI1 适用: 人, 小鼠, 大鼠 IHC, ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 97-112), (Extracellular) antibodyBAI1 适用: 小鼠 IHC, WB, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) antibodyBAI1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 60-350) antibodyBAI1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (C-Term) antibodyBAI1 适用: 人, 小鼠, 大鼠, 猴, Cow, 小鸡, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 691-740) antibodyBAI1 适用: 人, 小鼠 IHC, ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) (AA 31-350) antibodyBAI1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain-Specific Angiogenesis Inhibitor 1 (BAI1) antibodyBAI1 适用: 人, 小鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Brain-specific angiogenesis inhibitor 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Brain-specific angiogenesis inhibitor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BAI1 (Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
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别名
- Brain-specific angiogenesis inhibitor 1
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背景
- Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas.
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UniProt
- O14514
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途径
- p53 Pathway
抗原
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