Recombinant Topoisomerase II alpha 抗体 (AA 1431-1531)
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Quick Overview for Recombinant Topoisomerase II alpha 抗体 (AA 1431-1531) (ABIN7870710)
抗原
See all Topoisomerase II alpha (TOP2A) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 1431-1531
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原理
- Topoisomerase II alpha Antibody / TOP2A (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A recombinant partial protein sequence (within amino acids 1431-1531) from the human protein was used as the immunogen for the Topoisomerase II alpha antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the Topoisomerase II alpha antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the Topoisomerase II alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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别名
- Topoisomerase II alpha
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背景
- The topoisomerase II-Alpha isoform is a 170 kDa nuclear protein and plays an important role in DNA synthesis and RNA transcription, as well as chromosomal segregation during mitosis. Topoisomerase II-Alpha is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells, and has been shown to be over-expressed in many human cancers. Decreased expression of Topoisomerase II-Alpha is the predominant mechanism of resistance to several chemotherapeutic agents.
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UniProt
- P11388
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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