Complement Factor H 抗体 (AA 136-447)
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Quick Overview for Complement Factor H 抗体 (AA 136-447) (ABIN7870556)
抗原
See all Complement Factor H (CFH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 136-447
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原理
- Cfh Antibody / Factor H
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纯化方法
- Affinity purified
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免疫原
- Recombinant mouse protein (amino acids N136-T447) was used as the immunogen for the Cfh antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Cfh antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Cfh antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Complement Factor H (CFH)
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别名
- Cfh
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背景
- Factor H is a member of the regulators of complement activation family and is a complement control protein. This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- P06909
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途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
抗原
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