MAP3K7 抗体 (AA 131-160)
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Quick Overview for MAP3K7 抗体 (AA 131-160) (ABIN7870503)
抗原
See all MAP3K7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-160
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原理
- Map3k7 Antibody / Tak1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 131-160 from the mouse protein was used as the immunogen for the Map3k7 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Map3k7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Map3k7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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别名
- Map3k7
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背景
- Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
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UniProt
- Q62073
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
抗原
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