TRADD 抗体 (AA 126-151)
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Quick Overview for TRADD 抗体 (AA 126-151) (ABIN7870387)
抗原
See all TRADD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 126-151
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原理
- TNFR1-associated DEATH domain protein Antibody / TRADD
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 126-151 from the human protein was used as the immunogen for the TRADD antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the TRADD antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TRADD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- TRADD (TNFRSF1A-Associated Via Death Domain (TRADD))
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别名
- TNFR1-associated DEATH domain protein
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背景
- The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq].
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UniProt
- Q15628
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity, Hepatitis C
抗原
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