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Girdin 抗体 (AA 1231-1836)

This 兔 多克隆 antibody specifically detects Girdin in ELISA, WB 和 FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7870361
发货至: 中国
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Quick Overview for Girdin 抗体 (AA 1231-1836) (ABIN7870361)

抗原

See all Girdin (CCDC88A) 抗体
Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

适用

  • 59
  • 18
  • 6
  • 1
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  • 1
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  • 1
人, 大鼠

宿主

  • 60

克隆类型

  • 57
  • 3
多克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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This Girdin antibody is un-conjugated

应用范围

  • 37
  • 19
  • 15
  • 14
  • 14
  • 12
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 28
    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1231-1836

    原理

    Girdin Antibody / CCDC88A / GIV

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids K1231-D1836) was used as the immunogen for the Girdin antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Girdin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Girdin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

    别名

    Girdin

    背景

    Girdin, also called G alpha-interacting vesicle-associated protein (GIV), is a protein that in humans is encoded by the CCDC88A gene. This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    UniProt

    Q3V6T2
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