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RAD50 抗体 (AA 1224-1312)

The 兔 多克隆 anti-RAD50 antibody (ABIN7870345) specifically detects RAD50 in WB, ELISA, IF, FACS 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7870345
发货至: 中国
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Quick Overview for RAD50 抗体 (AA 1224-1312) (ABIN7870345)

抗原

See all RAD50 抗体
RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

适用

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人, 小鼠, 大鼠

宿主

  • 85
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克隆类型

  • 71
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多克隆

标记

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This RAD50 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 1224-1312

    原理

    RAD50 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids N1224-H1312) was used as the immunogen for the RAD50 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the RAD50 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the RAD50 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

    别名

    RAD50

    背景

    DNA repair protein RAD50, also known as RAD50, is a protein that in humans is encoded by the RAD50 gene. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

    UniProt

    Q92878

    途径

    DNA Damage Repair, Protein targeting to Nucleus
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