LRP6 抗体 (pSer1490)
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北京 101111
Quick Overview for LRP6 抗体 (pSer1490) (ABIN743558)
抗原
See all LRP6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1490
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human LRP6 around the phosphorylation site of Ser1490
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亚型
- IgG
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anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1198-1370) antibody
LRP6 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A3F5 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1546-1560) antibodyVerified LRP6 适用: 人 IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (C-Term) antibodyLRP6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 20-150) antibodyLRP6 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1531-1560), (C-Term) antibodyLRP6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01837 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 1531-1560) antibodyLRP6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (AA 981-1213) antibodyLRP6 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Low Density Lipoprotein Receptor-Related Protein 6 (LRP6) (C-Term) antibodyLRP6 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." in: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).
: "Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 96, Issue 2, pp. 249-59, (2016) (PubMed).
: "Urotensin II inhibited the proliferation of cardiac side population cells in mice during pressure overload by JNK-LRP6 signalling." in: Journal of cellular and molecular medicine, Vol. 18, Issue 5, pp. 852-62, (2014) (PubMed).
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: "FGF2 crosstalk with Wnt signaling in mediating the anabolic action of PTH on bone formation." in: Bone reports, Vol. 9, pp. 136-144, (2018) (PubMed).
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- LRP6 (Low Density Lipoprotein Receptor-Related Protein 6 (LRP6))
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别名
- LRP6
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背景
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Synonyms: ADCAD2, Low-density lipoprotein receptor-related protein 6, LRP-6, LRP6
Background: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity).
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基因ID
- 4040
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UniProt
- O75581
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途径
- WNT signaling, Tube Formation
抗原
-
