BCL3 抗体 (AA 118-307)
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Quick Overview for BCL3 抗体 (AA 118-307) (ABIN7870260)
抗原
See all BCL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-307
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原理
- BCL3 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E118-Y307) was used as the immunogen for the BCL3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the BCL3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the BCL3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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别名
- BCL3
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背景
- B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3 gene. This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. The BCL3 gene is mapped to human chromosome 19. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
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UniProt
- P20749
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途径
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
抗原
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