PDK1 抗体 (AA 114-436)
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Quick Overview for PDK1 抗体 (AA 114-436) (ABIN7870193)
抗原
See all PDK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 114-436
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原理
- Pyruvate dehydrogenase kinase 1 Antibody / PDK1
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids Y114-A436) was used as the immunogen for the Pyruvate dehydrogenase kinase 1 antibody.
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亚型
- IgG
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anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) antibody
KD Validated PDK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1190 unconjugated Recombinant Antibody
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) antibodyPDK1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 29-436), (Isoform 1) antibody (APC)PDK1 适用: 人 IHC, FACS, ICC, IF 宿主: 兔 Polyclonal APC
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 107-336) antibodyPDK1 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the Pyruvate dehydrogenase kinase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Pyruvate dehydrogenase kinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
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别名
- Pyruvate dehydrogenase kinase 1
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背景
- Pyruvate dehydrogenase lipoamide kinase isozyme 1, mitochondrial is an enzyme that in humans is encoded by the PDK1 gene. Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.
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UniProt
- Q15118
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途径
- PI3K-Akt Signaling, RTK signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effect
抗原
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