PDK1 抗体
Our Local Distributor
北京 101111
Quick Overview for PDK1 抗体 (ABIN2856238)
抗原
See all PDK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- Based on sequence homology, this antibody may cross react with other PDK family members.
-
交叉反应
- 人
-
产品特性
-
Rabbit polyclonal antibody to PDK1 (pyruvate dehydrogenase kinase, isozyme 1)
PDK1 antibody [N1C3] -
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein encompassing a sequence within the center region of human Pyruvate dehydrogenase kinase 1 / PDK1. The exact sequence is proprietary.
-
亚型
- IgG
-
-
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) antibody
KD Validated PDK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB1190 unconjugated Recombinant Antibody
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 107-336) antibodyPDK1 适用: 人, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Pyruvate Dehydrogenase Kinase 1 (PDK1) (AA 29-436), (Isoform 1) antibody (APC)PDK1 适用: 人 IHC, FACS, ICC, IF 宿主: 兔 Polyclonal APC
-
-
应用备注
- WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
说明
-
Positive Control: HeLaS3 , Molt-4 , human PDK1 transfected 293T cells
Validation: Overexpression
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- PDK1 (Pyruvate Dehydrogenase Kinase 1 (PDK1))
-
别名
- pyruvate dehydrogenase kinase 1
-
背景
-
Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation.
Cellular Localization: Mitochondrion matrix -
分子量
- 49 kDa
-
基因ID
- 5163
-
UniProt
- Q15118
-
途径
- PI3K-Akt Signaling, RTK signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Warburg Effect
抗原
-
