UPK1A 抗体 (AA 114-173)
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北京 101111
Quick Overview for UPK1A 抗体 (AA 114-173) (ABIN7870156)
抗原
See all UPK1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 114-173
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原理
- UPK1A Antibody / Uroplakin 1A
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 114-173 was used as the immunogen for the UPK1A antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the UPK1A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the UPK1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- UPK1A (Uroplakin 1a (UPK1A))
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别名
- UPK1A
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背景
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
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UniProt
- O00322
抗原
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