UPK1A 抗体 (AA 114-173)
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北京 101111
Quick Overview for UPK1A 抗体 (AA 114-173) (ABIN6938727)
抗原
See all UPK1A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 114-173
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原理
- Uroplakin 1A (Urothelial Differentiation Marker) Antibody
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特异性
- The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.
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交叉反应 （详细）
- Human.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant fragment (around aa 114-173) of human Uroplakin 1A (UPK1A) protein (exact sequence is proprietary)
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亚型
- IgG2b, kappa
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anti-Uroplakin 1a (UPK1A) (AA 114-173) antibody
UPK1A 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal UPK1A-2921 unconjugated
anti-Uroplakin 1a (UPK1A) (AA 114-173) antibodyUPK1A 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal UPK1A-2925 unconjugated
anti-Uroplakin 1a (UPK1A) antibodyUPK1A 适用: 小鼠, 大鼠 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 1a (UPK1A) (AA 114-173) antibodyUPK1A 适用: 人 IHC 宿主: 小鼠 Monoclonal 735M unconjugated
anti-Uroplakin 1a (UPK1A) (AA 117-232) antibodyUPK1A 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 1a (UPK1A) (AA 116-231) antibodyUPK1A 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uroplakin 1a (UPK1A) (AA 197-227), (C-Term) antibodyUPK1A 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: ELISA (For coating, order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Urinary Bladder.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- UPK1A (Uroplakin 1a (UPK1A))
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别名
- UPK1A
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背景
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UP1A, UPIA, UPKA, TSPAN21
Urinary Bladder.
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分子量
- 29kDa
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基因ID
- 11045, 159309
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UniProt
- O00322
抗原
-
