Mannose Receptor 抗体 (AA 1100-1400)
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Quick Overview for Mannose Receptor 抗体 (AA 1100-1400) (ABIN7870106)
抗原
See all Mannose Receptor (MR) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1100-1400
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原理
- Mannose Receptor Antibody / MRC1 / CD206
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纯化方法
- Protein G affinity
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免疫原
- A portion of amino acids 1100-1400 from human Macrophage mannose receptor 1 protein was used as the immunogen for the Mannose Receptor antibody.
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亚型
- IgG1, kappa
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anti-Mannose Receptor (MR) antibody
KD Validated MR 适用: 人 FACS, WB, IF (p) 宿主: 兔 Monoclonal 25GB2060 unconjugated Recombinant Antibody
anti-Mannose Receptor (MR) antibodyMR 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor (MR) (AA 22-131) antibodyMR 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5C11 unconjugated
anti-Mannose Receptor (MR) (AA 359-388) antibodyMR 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mannose Receptor (MR) antibodyMR 适用: 人 IHC, IHC (fro) 宿主: 小鼠 Monoclonal 7-450 unconjugated
anti-Mannose Receptor (MR) antibodyMR 适用: 人 FACS, WB, IHC, IHC (fro) 宿主: 小鼠 Monoclonal 15-2 unconjugated
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应用备注
- Optimal dilution of the Mannose Receptor antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Mannose Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Mannose Receptor (MR)
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别名
- Mannose Receptor
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背景
- CD206, also known as macrophage mannose receptor type C (MMR, MRC1L1 and MRC1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.
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UniProt
- P22897
抗原
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