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Mannose Receptor 抗体

MR 适用: 人 IHC, IHC (fro) 宿主: 小鼠 Monoclonal 7-450 unconjugated
产品编号 ABIN291690
发货至: 中国
  • 抗原 See all Mannose Receptor (MR) 抗体
    Mannose Receptor (MR)
    适用
    • 30
    • 23
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    • 4
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    • 1
    宿主
    • 23
    • 9
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    小鼠
    克隆类型
    • 25
    • 15
    单克隆
    标记
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    • 1
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    This Mannose Receptor antibody is un-conjugated
    应用范围
    • 21
    • 19
    • 9
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
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    Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.
    纯化方法
    Affinity purified
    免疫原
    Monocyte-derived dendritic cells.

    Type of Immunogen: Cells
    克隆位点
    7-450
    亚型
    IgG2a
    Top Product
    Discover our top product MR Primary Antibody
  • 应用备注
    Approved: IHC, IHC-Fr (1:50 - 1:500)
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Short term: -20°C
    Long term: -20°C.
  • 抗原
    Mannose Receptor (MR)
    别名
    Mannose Receptor / CD206 (MR 产品)
    别名
    CD206 antibody, CLEC13D antibody, CLEC13DL antibody, MMR antibody, MRC1L1 antibody, bA541I19.1 antibody, AW259686 antibody, MR antibody, mannose receptor C-type 1 antibody, mannose receptor, C type 1 antibody, MRC1 antibody, Mrc1 antibody
    背景
    Name/Gene ID: MRC1

    Synonyms: MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL
    基因ID
    4360
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