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Cyclin E1 抗体 (AA 10-176)

The 小鼠 单克隆 anti-Cyclin E1 antibody is suitable to detect Cyclin E1 in samples from 人. It has been validated for ELISA.
产品编号 ABIN7869690
发货至: 中国
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Quick Overview for Cyclin E1 抗体 (AA 10-176) (ABIN7869690)

抗原

See all Cyclin E1 (CCNE1) 抗体
Cyclin E1 (CCNE1)

适用

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宿主

  • 154
  • 37
小鼠

克隆类型

  • 109
  • 82
单克隆

标记

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This Cyclin E1 antibody is un-conjugated

应用范围

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ELISA

克隆位点

CCNE1-2587
  • 抗原表位

    • 32
    • 24
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    • 1
    AA 10-176

    原理

    Cyclin E1 Antibody / CCNE1

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 10-176) was used as the immunogen for this Cyclin E1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Cyclin E1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Cyclin E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Cyclin E1 (CCNE1)

    别名

    Cyclin E1

    背景

    Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

    UniProt

    P24864

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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