Recombinant Cyclin E1 抗体 (AA 10-176)
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Quick Overview for Recombinant Cyclin E1 抗体 (AA 10-176) (ABIN7869687)
抗原
See all Cyclin E1 (CCNE1) 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 10-176
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原理
- Recombinant Cyclin E1 Antibody / CCNE1 (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 10-176 was used as the immunogen for the Cyclin E1 antibody.
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亚型
- IgG1, kappa
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应用备注
- Optimal dilution of the recombinant Cyclin E1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the recombinant Cyclin E1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cyclin E1 (CCNE1)
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别名
- Cyclin E1
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背景
- Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.
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途径
- Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
抗原
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