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Recombinant Cyclin E1 抗体 (AA 10-176)

The 兔 单克隆 anti-Cyclin E1 antibody (Clone CCNE1-4935R) (ABIN7869685) specifically detects Cyclin E1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7869685
发货至: 中国
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Quick Overview for Recombinant Cyclin E1 抗体 (AA 10-176) (ABIN7869685)

抗原

See all Cyclin E1 (CCNE1) 抗体
Cyclin E1 (CCNE1)

抗体类型

Recombinant Antibody

适用

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  • 31
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  • 1

宿主

  • 153
  • 38

克隆类型

  • 109
  • 82
单克隆

标记

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This Cyclin E1 antibody is un-conjugated

应用范围

  • 145
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  • 11
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

CCNE1-4935R
  • 抗原表位

    • 32
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    AA 10-176

    原理

    Recombinant CCNE1 Antibody / Cyclin E1 (azide and preservative free)

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 10-176 was used as the immunogen for the recombinant CCNE1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the recombinant CCNE1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    -20 °C

    储存方法

    Aliquot the recombinant CCNE1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Cyclin E1 (CCNE1)

    别名

    CCNE1

    背景

    Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

    途径

    Cell Division Cycle, Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Mitotic G1-G1/S Phases
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