ube3a 抗体 (AA 1-860)
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Quick Overview for ube3a 抗体 (AA 1-860) (ABIN7869597)
抗原
See all ube3a 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-860
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原理
- UBE3A Antibody / Ubiquitin-protein ligase E3A
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids M1-E860) was used as the immunogen for the UBE3A antibody.
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亚型
- IgG2b
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anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 51-150) antibody
ube3a 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 836-865), (C-Term) antibodyube3a 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB4440 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 1-860) antibodyube3a 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 300-590) antibodyube3a 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyKD Validated ube3a 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 25GB1620 unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (Middle Region) antibodyube3a 适用: 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) (AA 83-234) antibodyube3a 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3A (ube3a) antibodyube3a 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB4775 unconjugated Recombinant Antibody
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应用备注
- Optimal dilution of the UBE3A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the UBE3A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- ube3a (Ubiquitin Protein Ligase E3A (ube3a))
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别名
- UBE3A
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背景
- Ubiquitin-protein ligase E3A (UBE3A) also known as E6AP ubiquitin-protein ligase (E6AP) is an enzyme that in humans is encoded by the UBE3A gene. It is mapped to 15q11.2. This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined.
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UniProt
- Q05086
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway
抗原
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