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HAP1 抗体 (AA 1-671)

The 兔 多克隆 anti-HAP1 antibody is suitable to detect HAP1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7869522
发货至: 中国
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Quick Overview for HAP1 抗体 (AA 1-671) (ABIN7869522)

抗原

See all HAP1 抗体
HAP1 (Huntingtin Associated Protein 1 (HAP1))

适用

人, 小鼠, 大鼠

宿主

  • 16
  • 3
  • 2

克隆类型

  • 19
  • 2
多克隆

标记

  • 18
  • 1
  • 1
  • 1
This HAP1 antibody is un-conjugated

应用范围

  • 17
  • 9
  • 8
  • 8
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-671

    原理

    Huntingtin-associated protein 1 Antibody / HAP1

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids M1-R671) was used as the immunogen for the Huntingtin-associated protein 1 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the Huntingtin-associated protein 1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Huntingtin-associated protein 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    HAP1 (Huntingtin Associated Protein 1 (HAP1))

    别名

    Huntingtin-associated protein 1

    背景

    Huntingtin-associated protein 1 (HAP1) is a protein which in humans is encoded by the HAP1 gene. Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    UniProt

    P54257

    途径

    Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
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