NBR1 抗体 (AA 1-665)
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Quick Overview for NBR1 抗体 (AA 1-665) (ABIN7869519)
抗原
See all NBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-665
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原理
- NBR1 Antibody / Neighbor of BRCA1 gene 1 protein
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-H665) was used as the immunogen for the NBR1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the NBR1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the NBR1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- NBR1 (Neighbor of BRCA1 Gene 1 (NBR1))
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别名
- NBR1
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背景
- Neighbor of BRCA1 gene 1 protein is a protein that in humans is encoded by the NBR1 gene. The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
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UniProt
- Q14596
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途径
- Autophagy
抗原
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