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PTBP1 抗体 (AA 1-504)

The 小鼠 单克隆 anti-PTBP1 antibody is suitable to detect PTBP1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF, IHC (p) 和 FACS.
产品编号 ABIN7869435
发货至: 中国
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Quick Overview for PTBP1 抗体 (AA 1-504) (ABIN7869435)

抗原

See all PTBP1 抗体
PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

适用

  • 79
  • 42
  • 39
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 71
  • 7
  • 1
小鼠

克隆类型

  • 40
  • 39
单克隆

标记

  • 39
  • 5
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  • 2
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This PTBP1 antibody is un-conjugated

应用范围

  • 60
  • 37
  • 22
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  • 16
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

3H12
  • 抗原表位

    • 8
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-504

    原理

    PTBP1 Antibody

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids M1-A504) was used as the immunogen for the PTBP1 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the PTBP1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PTBP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

    别名

    PTBP1

    背景

    Polypyrimidine tract-binding protein 1 is a protein that in humans is encoded by the PTBP1 gene. It is mapped to 19p13.3. This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.

    UniProt

    P26599

    途径

    Regulation of Muscle Cell Differentiation
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