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Recombinant PTBP1 抗体

The 兔 单克隆 anti-PTBP1 antibody is suitable to detect PTBP1 in samples from 人. It has been validated for WB, IHC 和 ELISA.
产品编号 ABIN7127781
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant PTBP1 抗体 (ABIN7127781)

抗原

See all PTBP1 抗体
PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

抗体类型

Recombinant Antibody

适用

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人

宿主

  • 81
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兔

克隆类型

  • 51
  • 51
单克隆

标记

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This PTBP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

8A1
  • 原理

    PTBP1 Recombinant Monoclonal Antibody

    纯化方法

    Affinity-chromatography

    免疫原

    A synthesized peptide derived from human PTBP1

    亚型

    IgG
  • 应用备注

    WB:1:500-1:5000, IHC:1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))

    别名

    PTBP1

    背景

    Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).

    Aliases: Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB

    UniProt

    P26599

    途径

    Regulation of Muscle Cell Differentiation
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