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PTBP1 抗体 (N-Term)

PTBP1 适用: 人 WB 宿主: 兔 Polyclonal RB40967 unconjugated
产品编号 ABIN1881702
发货至: 中国
  • 抗原 See all PTBP1 抗体
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    抗原表位
    • 12
    • 9
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-55, N-Term
    适用
    • 61
    • 25
    • 23
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 54
    • 6
    • 1
    克隆类型
    • 46
    • 15
    多克隆
    标记
    • 27
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This PTBP1 antibody is un-conjugated
    应用范围
    • 36
    • 24
    • 11
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    B
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human PTBP1.
    克隆位点
    RB40967
    亚型
    Ig Fraction
    Top Product
    Discover our top product PTBP1 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:4000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Osada, Uno, Mineta, Kameoka, Takahashi, Terao: "Ancient genome-wide admixture extends beyond the current hybrid zone between Macaca fascicularis and M. mulatta." in: Molecular ecology, Vol. 19, Issue 14, pp. 2884-95, (2010) (PubMed).

    Kanda, Gauss-Müller, Cordes, Tamura, Okitsu, Shuang, Nakamoto, Fujiwara, Imazeki, Yokosuka: "Hepatitis A virus (HAV) proteinase 3C inhibits HAV IRES-dependent translation and cleaves the polypyrimidine tract-binding protein." in: Journal of viral hepatitis, Vol. 17, Issue 9, pp. 618-23, (2010) (PubMed).

    Verma, Bhattacharyya, Das: "Polypyrimidine tract-binding protein interacts with coxsackievirus B3 RNA and influences its translation." in: The Journal of general virology, Vol. 91, Issue Pt 5, pp. 1245-55, (2010) (PubMed).

    Maynard, Hall: "Interactions between PTB RRMs induce slow motions and increase RNA binding affinity." in: Journal of molecular biology, Vol. 397, Issue 1, pp. 260-77, (2010) (PubMed).

    Xue, Zhou, Wu, Zhu, Ji, Kwon, Zhang, Yeo, Black, Sun, Fu, Zhang: "Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping." in: Molecular cell, Vol. 36, Issue 6, pp. 996-1006, (2010) (PubMed).

  • 抗原
    PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
    别名
    PTBP1 (PTBP1 产品)
    别名
    HNRNP-I antibody, HNRNPI antibody, HNRPI antibody, PTB antibody, PTB-1 antibody, PTB-T antibody, PTB2 antibody, PTB3 antibody, PTB4 antibody, pPTB antibody, Ptb antibody, hnrpi antibody, hnrnp-I antibody, vgrbp60 antibody, AA407203 antibody, AL033359 antibody, Pybp antibody, Pybp1 antibody, Pybp2 antibody, ptbp1 antibody, wu:fb99f12 antibody, zgc:110689 antibody, ptb antibody, ATPTB1 antibody, POLYPYRIMIDINE TRACT-BINDING antibody, POLYPYRIMIDINE TRACT-BINDING PROTEIN 1 antibody, T4P13.16 antibody, T4P13_16 antibody, polypyrimidine tract-binding protein 1 antibody, PTBP1 antibody, polypyrimidine tract binding protein 1 antibody, polypyrimidine tract binding protein 1 S homeolog antibody, polypyrimidine tract-binding protein antibody, polypyrimidine tract binding protein 1a antibody, polypyrimidine tract binding protein 1 L homeolog antibody, polypyrimidine tract-binding protein 1 antibody, PTBP1 antibody, ptbp1.S antibody, NAEGRDRAFT_80143 antibody, LOC100285404 antibody, Ptbp1 antibody, ptbp1a antibody, ptbp1.L antibody, PTB1 antibody, LOC100061673 antibody
    背景
    This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
    分子量
    57221
    NCBI登录号
    NP_002810, NP_114367, NP_114368
    UniProt
    P26599
    途径
    Regulation of Muscle Cell Differentiation
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