MRPL41 抗体 (AA 1-332)
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Quick Overview for MRPL41 抗体 (AA 1-332) (ABIN7869202)
抗原
See all MRPL41 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-332
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原理
- PIG3 Antibody / TP53I3
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids M1-Q332) was used as the immunogen for the PIG3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PIG3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PIG3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MRPL41 (Mitochondrial Ribosomal Protein L41 (MRPL41))
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别名
- PIG3
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背景
- Putative quinone oxidoreductase is an enzyme that in humans is encoded by the TP53I3 gene. The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q53FA7
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途径
- p53 Pathway
抗原
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